Product details
praziquantel
CAS NO.:55268-74-1
Packing：25kg drum
Details
Praziquantel is an anthelmintic agent belonging to the class of pyrazinoisoquinoline derivatives. It is identified by the chemical name 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one and has the CAS number 55268-74-1. Its molecular formula is C19H24N2O2.
Physical Properties
- Color: White or off-white crystalline powder
- Shape: Crystalline
- Odor: Characteristic
- Density: 1.22 g/cm³
- Melting Point: 136 to 142°C
- Boiling Point: 544.1°C at 760 mmHg
- Flash Point: 254.6°C
- Solubility: Soluble in chloroform, sparingly soluble in ethanol, and practically insoluble in ether or water
- Refractive Index: 1.615
Chemical Properties
Praziquantel exhibits stability under normal conditions but may be sensitive to prolonged exposure to light. It is not classified as a reactive substance but should be handled with care to prevent degradation. The compound does not have distinct acid-base properties but may exhibit chiral properties due to its asymmetric carbon atoms.
Synthesis Methods
The synthesis of Praziquantel involves a multi-step chemical process that includes the formation of the pyrazinoisoquinoline core, followed by functional group transformations and the final introduction of the cyclohexylcarbonyl group.
Uses and Functions
Praziquantel is primarily used for the treatment of parasitic infections caused by schistosomes, liver flukes, and tapeworms. It works by causing severe spasms and paralysis of the parasites’ muscles, leading to their detachment and death.
Safety and Storage
Praziquantel should be stored in a well-closed container, protected from light, and kept in a cool, dry place to maintain its efficacy. It should be handled with appropriate safety measures to avoid ingestion, inhalation, or contact with skin and eyes.